It seems like you are encountering an issue with Spine animations in Unity 6, specifically when using asset bundles. This problem might be related to the compatibility of the spine-unity runtime with Unity 6. The spine-unity 4.2 packages have been updated to be compatible with Unity 6, so ensuring you have the latest version of the spine-unity runtime could potentially resolve the issue. Additionally, if you have switched from the Built-In Render Pipeline to URP, make sure that your materials and shaders are correctly set up for URP. If the problem persists, it might be helpful to check if there are any errors in the console that could provide more insight into the issue.