Chris_solo Adding to Spinebot's answer, you could either:
A. Enable images compensation so that you can move the bone freely without also moving the vertices of your mesh, this is probably the fastest option. https://esotericsoftware.com/spine-tools#Compensation
B. Swap the weights with another bone temporarily so that the bone you want to move is not affecting any vertex. you may bind a new bone for this or use a bone that had no weights before. Then after moving your bone, you may swap the weights again to restore the influences.
https://esotericsoftware.com/spine-weights#Swap
Only then you will need to update the bindings to store the new binding position of your bone. (remember to do this in setup mode to avoid accidentally storing an animation pose) https://esotericsoftware.com/spine-weights#Update-bindings
You will need to update the bindings for every mesh that is influenced by the bone that you are moving.